A1CNow® Systems Offer a Variety of Options
A1CNow systems provide a fast and easy way of obtaining accurate A1c results in the office or home.  The A1CNow+ professional version offers a choice of a 10-count package or a 20-count package.  The home version, A1CNow SELF CHECK, comes in a convenient 2-test pack with all of the items you need to complete both tests.

The American Diabetes Association states that the use of point-of-care testing for A1c allows for timely decisions on therapy, when needed.[1]

More Efficient than the Lab

• Results in 5 minutes
• Small (5µL) blood sample
• Portable – use in multiple exam rooms
• Easy to use – minimal training required
• No maintenance

Certifications

• National Glycohemoglobin Standardization Program certified
• CLIA-waived
• IFCC Certified

PTS Diagnostics’ A1CNow®+ system is annually certified by the National Glycohemoglobin Standardization Program (NGSP).

• The purpose of the NGSP is to standardize glycated hemoglobin test results so that A1c results are comparable to those reported in the Diabetes Control and Complications Trial (DCCT) where relationships to mean blood glucose and risk for vascular complications have been established.

• In order to achieve NGSP certification, an A1c testing method must successfully complete rigorous testing requirements annually.

• A key component of the certification process is the Reference Laboratory Network. The network interacts with manufacturers of glycohemoglobin methods to assist them first in standardizing their methods and then in providing comparison data for certification of traceability to the DCCT.

• A1c test methods are awarded a ‘certificate of traceability to the DCCT reference method’ if they pass rigorous accuracy-testing criteria.[1]

a. Check HbA1c every month until HbA1c is <7%, and then at least every 6 months.
b. Although three oral agents can be used, initiation and intensification of insulin therapy is preferred based on effectiveness and expense.
c. See algorithm for initiation and adjustment of insulin.

Nathan D, et al. Diabetes Care 2006;29:1963–72. Reproduced with permission.

References

1. Nathan et. al. “Management of Hyperglycemia in Type 2 Diabetes: A Consensus Algorithm for Initiation and Adjustment to Therapy”, Diabetes Care 2006, 29 (8), pp. 1963-1973.
2. Inzucchi Ctal “Management of Hyperglycemia in Type 2 Diabetes: A Patient Centered Approach”, Diabetes Care 2012, 35: 1364-1379.

The table below shows the range or blood glucose that corresponds to an A1c value. The relationship between average blood glucose and A1c was derived through a combination of Continuous Glucose Monitoring (CGM) and 7- and 8- point self monitoring of capillary blood glucose. Corresponding blood glucose values and ranges below are updated as prior relationship between average blood glucose and A1c did not use CGM and relied on infrequent self blood glucose monitoring.[1]

References

1. Nathan, DM, Kuenen, Borg, R, Zheng, H, Schoenfeld, D, Heine, RJ. “Translating the A1C Assay Into Estimated Average Glucose Values” Diabetes Care Volume 32 (8), August 2008.
2. NGSP Website: http://www.ngsp.org/ifcc.asp

1. ADA Diabetes Care 2014; 37 (Suppl 1):S14-80
2. http://publications.nice.org.uk/diabetes-in-adults-quality-standard-qs6
3. IDF,http://www.idf.org/sites/default/files/IDF-Guideline-for-Type-2-Diabetes.pdf

Less stringent treatment goals than those noted in the chart above may be appropriate for patients with a history of severe hypoglycemia, patients with limited life expectancies, very young children or older adults, and individuals with comorbid conditions.[1]

References
American Diabetes Association. Executive Summary: Standards of Medical Care in Diabetes-2009. Diabetes Care, 32 (S1) 2009, pp. S6-S7.